021-51111890
购物车（）
sales@molnova.cn
Kinetin riboside
CAS No. 4338-47-0
Kinetin riboside ( N6-Furfuryladenosine;FAdo )
产品货号. M14476 CAS No. 4338-47-0
A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥243 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Kinetin riboside
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.
-
产品描述A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines; inhibits MiPaCa-2 cell proliferation with IC50 of 0.27 uM; induceds marked suppression of CCND2 transcription and rapidly suppresses cyclin D1 and D2 protein expression in primary myeloma cells and tumor lines, causing cell cycle arrest, tumor cell-selective apoptosis, and inhibition of myeloma growth in xenografted mice; also can activate PINK1 in cells independent of mitochondrial depolarization.
-
同义词N6-Furfuryladenosine;FAdo
-
通路Apoptosis
-
靶点Apoptosis
-
受体Apoptosis
-
研究领域——
-
适应症——
化学信息
-
CAS Number4338-47-0
-
分子量347.33
-
分子式C15H17N5O5
-
纯度>98% (HPLC)
-
溶解度DMSO: ≥ 29 mg/mL
-
SMILESO[C@H]1[C@H](N2C=NC3=C(NCC4=CC=CO4)N=CN=C23)O[C@H](CO)[C@H]1O
-
化学全称Adenosine, N-(2-furanylmethyl)-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Osgerby L, et al. J Med Chem. 2017 Apr 27;60(8):3518-3524.
2. Tiedemann RE, et al. J Clin Invest. 2008 May;118(5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26;285(13):9770-9.
2. Tiedemann RE, et al. J Clin Invest. 2008 May;118(5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26;285(13):9770-9.
产品手册
关联产品
-
DCH36_06
DCH36_06? as a bona fide is a potent p300/CBP inhibitor
-
ACBI1
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively.
-
CNX-774
CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).
